Carfilzomib is a novel, highly selective tetrapeptide epoxyketone proteasome inhibitor for use in patients with multiple myeloma who have received at least two prior therapies and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Researchers analyzed patient data from 10 countries. The team found a correlation between low vitamin D levels and hyperactive immune systems. Vitamin D strengths innate immunity and prevents overactive immune responses. The finding could explain several mysteries, including why children are unlikely to die from COVID-19.
According to the study from the Perelman School of Medicine at the University of Pennsylvania, combining the new breast cancer drug palbociclib with paclitaxel (Taxol) can shrink the tumors in nearly half of patients with estrogen receptor (ER) positive breast cancer.
Baloxavir marboxil, marketed as Xofluza, is a first-in-class, one-dose oral agent first approved by the FDA in 2018 for the treatment of acute, uncomplicated influenza in individuals 12 years and older, who have been symptomatic for less than 24 hours.
On April 17, scientists from the Sanford Burnham Prebys Institute of Medical Discovery, Hong Kong University, Scripps Research Institute and others published a study on bioRxiv that revealed 30 existing drugs that can prevent replicating of SARS-CoV-2.