Salcaprozate sodium (SNAC, CAS No.203787-91-1) serves as an excipient in drug formulations, acting as a chemical permeation enhancer (PE). It is employed to improve the oral absorption of macromolecules, peptides, and proteins like insulin for diabetes management, heparin for heart conditions, and cyanocobalamin to address vitamin B12 deficiency and anemia. This application of SNAC enhances the bioavailability of these substances, contributing to their effectiveness. Notably, SNAC has received FDA recognition as Generally Recognized as Safe (GRAS) for human consumption, ensuring its safety in pharmaceutical use.
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