Application: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
mPEG36-NH2 is a methyl-terminated PEG amine compound. Carboxylic acids and their active esters react with the amino terminus to form amide bonds. In addition, the amino terminus reacts with aldehydes and ketones to form Schiff bonds, which are reducible to secondary amines. Applications of mPEG36-NH2 include modification of acid-functionalized surfaces and free carboxylic acid groups on biomolecules.
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. Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; IBSN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.
. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.